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CASE REPORT
Year : 2017  |  Volume : 1  |  Issue : 2  |  Page : 54-60

Osteolytic lesion of the mandible in a 42-year-old female


1 Division of Oral and Maxillofacial Surgery, College of Dental Medicine, Western University of Health Sciences, Pomona; Department of Oral and Maxillofacial Surgery, Loma Linda University Medical Center, Loma Linda, USA
2 Division of Oral and Maxillofacial Surgery, Alameda Health System, Highland Hospital, Oakland, USA
3 Division of Oral and Maxillofacial Surgery, Alameda Health System, Highland Hospital, Oakland; Department of Oral and Maxillofacial Surgery, Dugoni School of Dentistry, University of the Pacific, San Francisco, CA, USA

Correspondence Address:
Jeffrey Allan Elo
Division of Oral and Maxillofacial Surgery, College of Dental Medicine, Western University of Health Sciences, 795 E. Second St., 3rd Floor, Pomona, CA 91766
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijcpc.ijcpc_15_17

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A case of metastatic breast cancer with medication-related osteonecrosis of the jaws is described in a 42-year-old Hispanic female who was previously unaware of a preexisting breast carcinoma. Radiographic examination demonstrated the absence of visible lamina dura and periodontal ligament on teeth in the affected area; while clinical examination demonstrated a moderately diffuse swelling of the right mandible and vestibule without distinct masses. Microscopy revealed disordered lesional cells with moderate variations in nuclear size, shape, and chromaticity, with a low mitotic index. Also noted were segments of necrotic remodeled resorbed lamellar bone showing enlarged empty osteocytic lacunae, a serrated external surface, adherent granular basophilic bacteria, and a fibrinous exudate with neutrophils.


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