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Year : 2020  |  Volume : 4  |  Issue : 1  |  Page : 10-12

Hepatosplenic T-cell lymphoma: A clinical diagnostic challenge

1 Department of Histopathology, SRL Ltd, Fortis Escorts Heart Institute, New Delhi, India
2 Department of Gastroenterology, Fortis Escorts Heart Institute, New Delhi, India

Correspondence Address:
Nalini Bansal
SRL Ltd, Fortis Escort Heart Institute, Okhla, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijcpc.ijcpc_4_20

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Hepatosplenic T-cell lymphoma (HSTCL) is a rare variant of T-cell lymphoma and comprises less than 5% of all peripheral T-cell lymphomas. These lymphomas have an aggressive course and dismal prognosis. We report a case of a 28-year-old male who presented with repeated episodes of fever and abdominal pain. Ultrasonography revealed hepatosplenomegaly. Liver biopsy performed showed sinusoidal lymphoid cell infiltration of the T-cell immunophenotype with aberrant antigen loss. The case was finally diagnosed as HSTCL.

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